Transcript of Episode #94 Dylan Gemelli Guest Appearance on the Biohacking Beauty Podcast! An epic discussion on peptides, botox, skin care, exosomes and more!! New

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Okay, finally, Dylan, welcome to the Biohacking Beauty podcast.

It's great to be here, brother. It's always a pleasure to talk with you, man.

Yeah, I mean, we haven't known each other for a long time, I think, like a few months, and I'm ashamed to To admit that I didn't know of your existence before, and I didn't know you're so popular, but you are a very popular, I think, information biohacking purveyor. And I'm wondering, why... It's a weird question, but why do you think that is? What do you think made you so successful within that community?

I started doing YouTube videos almost 15 years ago, and immediately, I I think it was, one, was the topic I was willing to discuss, but I think, two, it's the authenticity because it's just you get what you get. I don't play a role. I don't play a cartoon or a person. It's just straightforward. I really try to not only keep it real, but I like to just talk about such a variety of things, and I'm really multifaceted. I was in this industry, and it was like, I was screaming to be let out and to do so much more. I have a lot to offer, I think, in a lot of areas. And another thing with the conversations I have, I'm a good talker, communicator. Everybody's good at something, and that just happens to be where I'm good at, man. I think that I'm able to get people to listen to what I have to say, and I'm really good at spotlighting other people. It's important when you have a conversation that it's a two-way thing. There has to be good relatability and credibility, and I don't know, man. I am a very spiritual-driven guy, and I just try to do whatever God is telling me to do at this point.

It's not about Dylan anymore. It's just like, I'm trying to do the best I can for everybody, and I think it's resonating. I really do.

Yeah. Do you have a lot of people coming to you and asking, Hey, I actually don't know where to start. What is the direction I need to go and take ownership on my health or something like that?

Yeah. I mean, one of the things that I've always gotten from the moment I ever started doing anything. How do I lose weight? Or where do I start? What do I do? There are certain aspects with health that are very standard. Get plenty of rest, Proper nutrition and things. But then, you know this, there's different skin types for what you deal with. Everybody's got a little different thing they may need. For me, it's like, well, structurally, there's so many factors, your age, your genes, different aspects of family history and health. I always tell people, look, let's start here. Let's get that rest. Let's get outside in the morning, get some sun. Let's walk. Let's have good state of mind. Because everything is mind body connected. You know this, too, and I'll relate it back to skin again because it's very relatable to what you do. It shows in your skin and your face when your health is off, and when you're not resting. It's an accumulation of things of non care. And so I always really try to start as basic as I can with people and not make it complicated or hard so they don't get scared.

And then we just roll, man. And I'm always about accountability, but then also congratulatory on people that do well. Just understand, complacency is a terrible word. So when you're doing well with something, you don't just stop. You always celebrate it, but then move on. Just keep going because there's always something better you can do.

Yeah, I agree. To your point, you can't unscramble an egg. If things have a falling apart and the base is not there, you're not getting your sleep, you're not getting your nutrition, whatever that is. Your gut lining is destroyed or you have a bad relationship with insulin. These are things that you can do all the fancy biohacks, but you're working against something that is so intrinsic, so fundamental that in nothing, in There is no steroid you can take that beats bad sleep.

No, no, there is none. You know that term, and I am enthralled in the biohacking sphere in the world, but people can be, and I had a good laugh with Dave Osprey about the polarization of the word, and he said it's so stupid to think that. But you have to correlate it with people look at something like that and they think, Oh, wow, you got to spend 20 grand on technology, and you to do all of these crazy things, and that's just not it. It's such a wide-faceted word that has so many definitions to it that you just have to get around and realize that it just comes down to your health and taking care of yourself and doing it on your own, not relying on doctors and everything. They're necessary, they're needed. But no one's going to watch you 24/7. You know what I mean? You, me, everybody else, we're responsible for what we eat, how we sleep, how we live our life. And that's it. It's just figuring that out.

First of all, I think it's very hard for people to understand that more money doesn't equal more results per se, and that getting 50% there is significantly more simple, or even 90% there is significantly more simple and more affordable than getting each % past 90% as far as optimization. That, by the way, applies to many parts of physics. It also applies to your electric vehicle. Charging your battery to 80% takes significantly shorter than charging the next 10 or 20%. Yeah. And by the way, financially as well, your red light is like 500 bucks, whereas some of those crazy immortal beds is 125 bucks. But the difference in health optimization is like 2 %. That's right. So the problem is that people are saying, I'm in a really bad spot. I have a lot of money. Let's say I've sacrificed my '20s, '30s, '40s, my health to gain a certain level of finances. And now I want to buy the $100,000 thing because I think it's going to overhaul my health. And that's an unhealthy I think with health optimization as a whole, but also with investment in that.

I have to agree. I'm a finance business guy background. Before all of this, I always go back to making your dollar go as far as it can and understanding that there are multitudes of ways to do very good, healthy things that don't have to be this big name brand. Look, I've lived in that world in that trap. I was a model and an actor for a very long time, and I lived a very vain, ignorant, idolatry-type life to things, to clothes, to all of this stuff. I realized, What am I doing here? What is this Gucci shirt doing for me that the polo shirt isn't doing? It's a $700 difference. What is it? Is it a stigma? I don't know. But once I got a little bit older and realized that you can do so much more with so much less if you just do it wisely and carefully. It a little bit goes a long way often in everything that we do. Now, there are certain things that I would always say spend more money on, spend the extra money on the good food, the things that you're putting on your body, the skin cares, the things that are safer, the things that are proven.

That's just coming down to what's the most important to you. You do without the alcohol and spend it a little bit extra on the food. Things It's like that where I can't fathom not taking care of yourself first and balancing that out. It's like this. When you say, Oh, I don't have time to work out, well, go to bed a little bit earlier and get up a little bit earlier. What's your priority here? What are you doing later at night that you could cut out instead? It's priority, brother. It always comes down to what's the most important to you. When you find what it is, you'll make it work.

Yeah, definitely. The one thing that I would say that you don't want to try the nickel and dime right now in the health world, I think, is peptides because... Oh, yeah. I mean, we've said it in this podcast a few times. This is still when you buy peptides today in the United States, you're basically buying them for research only. Not only that they're not regulated, regulation says that you shouldn't be using them. So if you're using them, it is going Coming against regulation per se. And that is a loophole really anyone could use. You could sell sawdust in polypeptides, for that matter. It's as legal as selling you the real thing. So, yeah, it's extremely... This is the one area that I wouldn't try to save 10 bucks on a vial, right?

I don't know how much you know about my background, but I discovered peptides in 2011, working with different companies that said, Well, we'd like you to start doing some research on research chemical companies. I have probably some of the most intricate knowledge of any human that you will ever find in terms of the underground research, Sarm's Peptides Neutropic World, because I've been around it for 15 years, and I'm talking knee deep. I know exactly every little bit and piece that goes on within that community. It's like for every 10 to 20 new company that pops up, that they pop up consistently, and I'm talking daily. If you do your research and know it, for every 10 to 20 of those, one to two will actually do intricate testing. Within those one to two, maybe one will actually do it consistently every time they get products, because every time these products come in, they're coming in from China, and they're sending you fake COAs, which stands for certificate of authenticity for anybody that doesn't know what that means. I mean, if they're good at faking Louis Vuitton and Gucci bags, I'm pretty sure that they can put a paper together and make one.

I mean, dude, I can go on Adobe and make you one right now. Give me 20 minutes and 500 bucks, and I'll have it to you, right? It's for a waste of my time. But And here's another thing that I'm sure that some people aren't aware of. A lot of these testing companies, they get bought out on page two. One of the biggest ones just got busted out about, I don't know, six months ago that everybody called the gold standard, that they were taking money to put out fake certificates for people. So it's very difficult to get through. And there is that fear because it says for research purpose only because it's the only way you can sell it. And the FDA, picks and choose who they want to go after. Exactly.

Actually, if you're very good, you're probably going to get shut down.

Yeah. Trust me when I tell you, they can get in Google Analytics, see who's getting all the traffic, who's spending all the money on the ads. They know how to do all of this. It's very simple. Once again, I could go get that done for us in 20 minutes. You see these people, A, spending money, putting out fake reviews because all those review sites are fake. We know this. These press releases, they're fake. If you go down and read where they're coming from. So there is such an abundance of bad actors out there that ruin it for the couple that do it right. And then they make it to where it's this danger zone, and rightfully so, because Because they're hurting people because all they care about is making a couple bucks. Correct. Yeah. So, you know.

I think it's even to make it think it's scarier a little bit. I think we should all remember what happened. I think it was already 10 years ago with GMC, where people in Long Island, elderly in Long Island, were getting liver failures. And they found out that B12 pills that GMC was selling were tainted with anabolic steroids from the contract manufacturer that was making the product for GMC. And then obviously faking tests, things like that. And people, again, elderly people who were taking B12 supplements were ending up in the hospital with liver failure. It's not to excuse anyone, but it's actually very difficult to be, even if you're well meaning, to be at the top of your game all the time as a retailer of those research compounds, of those peptides.

Well, it's pricey to go get stuff tested consistently. I can tell you right now that every time that you go as a research company, let's say that you get in a peptide powder and you want to go have it tested. Well, every time you get a batch in, it's costing $2,000 and $300 to test. You start, a lot of people will go, Oh, I see the cost of the raw materials, but they've never ran a business. When you go up and down a business and see all the expenses that go along with it, the packaging, the employees, the facilities, by the time you're done, the margins are so low, so they're cutting every quarter they can. You got to remember, too, when they get shipments sent over, a lot of times they get picked off, so they're losing the money they spent on it, too, because the border But also, again, how many conversations like this are happening?

I think it's one to a hundred of people who are going to go online and look for peptides even has this faintest idea, never mind getting 5, 10 minutes into a conversation about the dangers of of these companies or of testing, how many people actually know that they should be not nickel and diming it? You are definitely... You can't charge $100 when someone charges 30, and because you've decided to have all the testing, you will be making less money. That's a bottom line. It's very difficult to say, I'm going to make less money over time, obviously.

Well, especially when you see other people making a lot or you have made a lot, and then something happens. I mean, I could write a complete novel on this, and people that would read it would be completely astounded at everything that I know that goes along within this whole system. And as I mentioned earlier, the thing now is it's like, well, somebody sees somebody else doing it, and these companies just keep popping up, and they keep popping up. I know because I coach peptides, I've worked with these companies, and so it's part of my daily research. I do research on everything that I'm a I'm part of. That's one of the aspects of what I do. I study every part of it, not just mechanisms of action and how things work, but I also look at, well, where are all these things coming from and how is it changing and how is it evolved from 2011 to today? When I started, there was six or seven peptides in the research world that you could pick from, and that's it. I've watched this growing to this monster and seeing how it's changed, because when we were doing it, it was only bodybuilders were looking at these.

They were a joke to bodybuilders because in comparison to steroids and sarms, they were like the third level where you're not really gaining any much muscle. Seeing what they become and how many different parts of our life and our well-being. It's been such a pleasure and fascination for me to watch and be a part of and seeing more doctors and people talking about them, and seeing that it's for your mitochondria, your brain, your skin. It's not just about your growth hormone and getting tan because that's all there was back then was melanotan and THRPs. It's been pretty damn cool to watch and to be a part of.

Before I'm asking you about specific combinations and peptides, do you have any guidelines to choosing a good supplier, or do you have just names that you like to work with? How do you suggest someone goes about it? Let's say we inspire them to go down that rabbit hole.

I actually have worked with a company closely because I know the owner. It's funny because, and I'm not trying to answer this like a politician, but I want to just give a little bit of background on what I've seen. When I started, I was like, Man, I can't start promoting stuff I don't know about. I studied them and learned about them. These companies were so new at the time. They were making stuff in their houses, in their kitchens, literally. No lie. They did not have facilities or anything. Plus, it was so scary with the FDA. A lot of these places, I was actually seeing, how are they even sanitary? Anyway, I got really sought after because I had millions of subscribers on YouTube listening to me, and anybody I promoted was making hand over fist. And by the way, my channels got shut down back then, but that's a different worry. Yeah, twice. And I had millions of subscribers twice. You can imagine what that felt like. So I rebuilt multiple times here. But anyway, I ended up finally, after being partners in some, I never ran my own, but I helped start companies because of my influence.

Well, I met a company in Arizona, and it's called Umbrella Labs. He flew me down there, and he has a million-dollar facility, state-of-the-art machinery. I mean, I'm talking this guy was on a whole different level of anything I'd ever seen. True manufacturer, true beautiful setup, everything tested, all these high-end refrigerate. I'm talking everything. They had their testing done on multiple places, so it was double, triple-checked. They're spending a lot of money, but their prices are a little higher. That's the place that I know because they've been around 10 years, and I still give him advisory. I don't want to have my part, a role in these companies. I'm a little scared for me personally, but I do have a friendship, and I do have my own personal use. If I ever want to use something that you can't go get prescribed from a compounding pharmacy because you know you can only get so much. But that company is called Umbrella Labs. That's really the only one that I will even consider if I do use anything because they've been around so long. I know because I've been there multiple times and seen how they do everything.

But those are few and far between. Here's what a lot of these places do, Amate, is they source this all stuff out. So a lot of the places that you see and that you buy from, you're buying the same thing from 20 different companies. People don't know that. So here, I'm a sneakerhead, right? So if I go to Champs or if I go to... They're all the same. Foot Locker, you'll notice all have the same stock and everything because it's the same. They're all getting it from the same place. Well, these places, they'll go through. You think, Oh, I got such great quality from so and so. It's like, Brother, you're getting the same thing from them that you are from here.

That's the NMN game. Yeah, NMN. The top 2,000 retailers of NMN supplements in the United States are getting it from one supplier in China.

Yeah. It's bad. It's really bad. What you just said is so true of so many of these places. They either have the same exact Chinese supplier that goes direct to them, or they have a company here that does their white labeling, and they get it all from the same. It's like all it is, it's the same product in a different bottle, different label. That's it. That's it.

Yeah, so that's actually great. I mean, to be honest, it's also good. It's refreshing to get a straight answer is like, Hey, this is the one I know, this is the company I've been working with and I've seen results. Because it's hard to go on a limb. To those who don't know, there was one big company that every doctor used to work with. They were called TaylorMade. People might see advertisements now for a direct-to-consumer product called Infiniwell. That's the same company.

Yeah, I know it.

If anyone ever had true diagnosis agnostics test done, that's the same company, basically. But the FDA just waited, bided their time. Then they were juicy and interesting enough, and the FDA just rated them like one day and basically He tore that company down. So it's scary to say, to associate yourself with anyone in that field. So that says a lot, actually, which is great. So let's talk a little bit about actual peptides that are going to result, at the end of the day, more broadly with longevity, but also with skin. I'll start us with something interesting that you said. And it's not a secret. Many people go on this path because they have some unsuccessful path. Their path is unsuccessful as far as their body composition. Well, before GLP once, many, many, many peptides that we now think of or that we now are using for longevity actually started as weight loss peptides. They weren't very successful. They were successful in other areas. But many of those started like that, right? Botzd or 5amino1-MQ. More broadly, let's talk about peptides that are just improving your overall health. What is your approach to them? How would someone use those tools just to get a better baseline of health, if you would?

I always do a little quiz on people that come to me for general health. A lot of times, a lot of the same symptoms in the age ranges that I deal with, and I always look at blood panels first, mind you, but generally, ipamorelin and CJC-1295 are often combined and used together. And those are going to be ones that I am looking at. They do so many different things, and a lot of it will revolve. And if people don't know, they're like growth-releasing hormone peptides. What that means is when you take exogenous HGH, you're taking actual HGH, you're taking a synthetic form to get more human growth hormone. Human growth hormone. Yes, human growth hormone. With a releasing hormone peptide, you're allowing your body to naturally release it on its own. It's actually a heck of a lot better because you're having your body do it on its own than taking something like, I'm on testosterone replacement therapy, so I'm taking it exogenously to get my body to produce it. But these are two that are the most commonly prescribed. If you go to a clinic or things of that nature, more often than not, and this, especially a few years ago, these were the ones that you were going to get prescribed the most.

There's multitudes of studies that I'd have to pull up for you on what they do because these have been around for so long. These were actually around back in 2011 when I was talking about that. But there's things that go so far as to thyroid function, heart function, what's... Intestin function. There's other things because people look at these and they're like, well, they help with lean muscle. They help with your sleep. They do provide what you would call some anti-aging type benefits because they do... I mean, secondarily, you're sleeping better. It's improving your skin. But these are your basic ones that I look at. But then what's the most popular thing everybody talks about? It's BPC, right? So everybody talks about BPC-157. But when everybody looks at it, I guess most people that look at it, they're going after it for the healing. Okay. So the main reason that it got so popular so fast was because so many athletes are using it, and they're speeding up their healing. I can't tell you how many different athletes come to me. I've got this severe injury and a torn ACL or something serious. They think in their head that this is going to make them heal in three months like the Terminator.

And I'm like, just temper your expectations. But it does speed up recovery and enhance it. It's called body protective compound. Of course, if you learn about it, but it does so many other things.

It's really cool. I think it's important. Sometimes we can trace down a peptide for where it comes from. Then things are like, Oh, that makes a lot of sense. So first of all, anyone who's listening to the podcast know that I say that peptides are like computer codes. They're basically the ways that our body can relay signals around. And the thing about BBC 157 is that it's a natural computer code in our body to heal the gut lining when it's getting damaged. So guess what our gut lining is made out of Mostly it's collagen. And that's why when we inject it into the... We can bypass the gut because you could take it also... We're talking about 2011. I don't know when integrative peptides, shout out to integrative peptides, came out with a pill version. But there are pill versions of it. There are oral versions of it. They weren't less well for overall body healing.

That's right.

So when you bypass the gut and these peptides come around and find areas of inflammation to correspond with, what they're saying, in other words, is, Hey, let's lower inflammation. Anything that they think they were giving them a little bit of life, but anywhere that they think they're their gut and like, Oh, my God, there's an injury here. They're going to do what they're doing in the guts. Like, hey, let's bring more collagen here. Let's grow some blood vessels. Let's lower inflammation. Let's resolve inflammation more than lower, which is way more important. So it's really cool to understand where they're naturally at, their natural habitat, if you would, and what they do in other habitats because they think that they're there. So that's a really cool peptide, which now, by the way, is getting roped into this. I just saw some famous model go to her integrative doctor, and he was giving her GHKCU, BPC 157, and TV 500 as some a glow. Glow, yeah. Yeah. So, yeah, it's being used a lot for beauty as well.

So there's a product called Glow, which you just mentioned, and then there's one they call Clow with a K because it has KPV in it as well. Those are the two big ones going around right now. I am a very big fan of KPV, and I love that combo. I do want to touch on something real quick that you brought up that's very important when we were talking about the capsule or the oral form of BPC, because I know a lot of people don't like to inject, and it does get annoying. But I do want to make it very clear that injection is by far the most superior form of it. Now, I'm not sure if you're aware of this, and I wanted to bring this up before I get into some oral data, but there is the company I brought up, Umbrella Labs, they did a cream of BPC and TB 500, and that's what I use. And that is so easy and so nice because it's very efficient without the injection because, man, I've been injecting so long, I get sick of it, and it is annoying, so I do get that for people.

But I do want to make sure people do understand that's going to be the... You're going to have the highest efficacy. The capsule started getting a little bit more popular, or at least coming around right after around COVID, a little before that, where people were experimenting with it, and they got more prevalent a couple of years ago. I don't like it because there's really low bioavailability because of the breakdown of the stomach acid, right? Yeah, right.

Today's, yeah.

I'm a data guy. I know you're a data guy. There's really not much research aside from just people and you know how people can imagine they're doing something that maybe not.

To be honest, I'm a little worried because they're starting to incorporate ingredients there that delay its breakdown. Yes. And that's actually where she'll be bad for your gut to have these ingredients running around.

I agree. And that's the concern. And also, you're depending and hoping that these places that are pressing the capsules actually know what they're I'm putting in there. I've seen firsthand how some of these people press, and it's scary. When I saw that, I was like, Okay, I'm never ordering any capsule of any kind from any company whatsoever. It took me a long time to get over it. Injectable is going to have highest bioavailability, and you get a direct action when you inject it into an injury of wherever it's injured or inflamed, right? Then there's good veterinary and animal studies that were done on it.

But Yeah. I would say one thing since we're also talking about a compound, and I love the fact that you were like, Hey, this is a compound. This is the best way to consume it. I think consistency is key here. To understand you're going to a 90 day, six loading phase, like six weeks before you really feel anything. Then you're running another six weeks, let's say, of enjoying the benefits. Then you need to not do it for a couple of months. There are other ways. You mentioned oral or you mentioned cream, but I'm starting to see two things that I think are less... They're a little disingenuous with most peptides. First is IVs, and the second is straight to the face injections. And both of those, they just don't follow the mechanism or the data behind how you should load those. So I'll let you talk about IVs, but I can tell you what I've seen with estheticians or practitioners injecting them into the face as a a rejuvenation treatment. Peptides don't work like... You can't just do it once a month and expect anything to happen. So injecting it daily, using it daily, building it up in your system is the way to go rather than going to someone to inject it into you once a month.

So So when you take steroids, specifically, testosterone, it comes with what's called an Ester chain, right? So that's like a delayed onset release. So on TRT, ideally, you take testosterone, cipionate, because it's like a seven to eight day half life. And theoretically, you take it once a week, and you're good throughout the week. I don't prefer that because you still have this peak and a trough. And so when you hit that trough four or five days into the week. So if I go get my blood panel test a day of injection as opposed to five days later, it's like, whoa. And that can give you an up and down feeling. Well, these peptides, they don't have these ester chains attached, and they don't have long half-lifes. So if you don't take it consistently, well, what happens when you're not consistent? You have inconsistent or negligible result. And they market all of these things and these methods and these strategies that they really don't know about, and people are easily manipulated, and rightfully so, because people don't have 70 hours in a day to research every little thing. You're going to take... Unfortunately, a lot of people, more often than not, are just going to take the word of it of what they're told.

That's part of the reason I do what I do. I try to touch on so many different areas is because I'm trying to put out information to help people have it readily available to them where they could click, listen, and go, Wow, I better not do this. It's important that we have conversations like this because people don't know where to go for this info. We were talking earlier, there's a lot of sites out there that are saying things that aren't true just to get you to do whatever. Having a credible, loud voice, and when I say loud, not obnoxious, but a heard one, it's important, man. And that's why I love this conversation we're having, because it's bringing to light a lot of stuff that most people... I would say what you said, 99% of the people, 99. 5, would have no clue about most of the stuff we're talking about, underground, especially.

Yeah. And even in this conversation, we have to almost like bob and weave between, Hey, you should use this. This is great. These are the results that you can get. Hey, this is, by the way, what you shouldn't be doing. But look over here. This is also To be honest with you, I wish this podcast, obviously, we're a skincare company that's making a podcast. But a lot of people, including people within our own company, especially our marketing team, were like, Hey, you're not talking about products enough. I'm like, Look, there's so much information we have to provide to people. We almost are a podcast company with a monetization excuse to make sure that we have information, that we can support that information. But I do want to go back to Glow and Clow because I have seen them. I'm actually extremely surprised by the explosion or by the, first of all, amazing results, but also explosion in interest to these, no pun intended, these umbrella peptides, right? Yes. So we talk about BPC-157. Obviously, the hero ingredient in is GHKCU, copper peptide, right?

I love GHKU, man.

Dude, we incorporate it in a lot of products, and we are deep into research because, again, as you said, creams are great. They're just never as effective as injections holistically. Half of what we do is we try to figure out how to complex it with other peptides to make it more effective. But let's talk about why would that be a hero ingredient to inject? What's going on there that makes it so effective?

Yes, yes, yes, yes, yes, yes, yes. I really got more into GHKU about two years ago. Just a little bit of background on me, I am not anywhere even in the realm of skin expert like you whatsoever. However, I've been modeling since I was 23, and so I have been taking care of my skin way more than you would see most women take care of their skin. I do have a little bit of So my point in saying that is that anything that has anything to do with skin, I'm ultra-fascinated, right from the jump. So of course, this was appealing to me when I first started to take notice of it. And it's not in It's not in my supreme wheelhouse because I've studied hormones for so long, but I do know a great deal about it. So into it, anti-aging, I think, is the obvious that people are looking for with it when they're first attracted to it, right? Because it's It's going to stimulate collagen and elastin production, and that's going to really help improve your firmness, your skin firmness, just going to help reduce wrinkles. Skin regeneration, though, is another thing that it does that is appealing to people because it can repair damaged skin cells, and it's going to improve your structure of your skin.

So you'll notice that. And then it's got antioxidative protectants in it. So it's going to protect your skin cells from oxidative creative damage and stress. And it can improve the skin texture, which is another thing that you notice. Helps smooth out rough skin.

I'll tell you what, one thing that is another win into the call, another checkmark to the column of injectable versus topical is with GHKCU, topically, you need to pick your poison, where if you go over, let's say, 2% to 3% 2%, if you are buying it from a less reputable source, 3% if you're buying pharmaceutical grade. Towards 5%, you're going to start stimulating hair growth. And so there is a It's a payment to how much you can have in skincare. When you inject it, you are actually getting great hair growth results or you're getting hair health results, scalp health results, without growing hair in places that you wouldn't want. I think there's that, which is cool, where you could get into this looking for skin rejuvenation, but also getting fantastic hair alongside it.

Absolutely. And beyond the skincare, there is some other benefits, and that's why it's incorporated into this, because there is wound healing as a benefit that people probably don't even think about, right? And like you said, there's anti-inflammatory there, too. So that's why these are very synergistic when they go together. This wasn't just something that just got pieced and thrown together. There's a reason that there's a function of either all three or all four, depending on if you're doing glow or clo. And if I may, if you don't mind, I would just like to touch on KPV real quick and how it fits into this equation. So one of the things that I love about KPV is that it heals and supports gut health. You brought it up at the beginning. I constantly Let me bring it up. I've had so many experts talk about gut health, and it's finally becoming more prevalently understood on how serious this is in terms of our health. I would argue that mitochondria, cellular function and health, and then gut are the two things that are either going to make or break our life, right? I mean, in reality. We're talking about gut health, but then reduction of inflammation with KPV, immune balance skin conditions, so psoriasis, dermatitis.

There's benefits in skin conditions like that. What's another one? Eczema. I don't want to talk about COVID by any stretch of the imagination.

Rosacea as well, by the way, Before you mentioned it, rosacea. I mean, I've seen crazy results with KPV, even topical KPV. Yes. Even people reconstituting it into just sprayers and spraying it on their face.

Yes. There's been people, and this is not just COVID-related, but people with long COVID, because I don't want to do that. I don't want to get in that. But I'm just speaking on what I've seen. Post-viral inflammation, fatigue, people are using it to help with all of that, and it's helping. I'm not saying it's a cure for COVID by any stretch, but I'm saying it's helping. If you ask me, I would always opt for the one that has KPV in it. Always. I would never leave that out. I think I have a series on the top 10 peptides you don't know about but need to know about that I'm working on, and this is directly in there. It's one of my favorite topics to even get into. I think that it is going to be sooner than later, one of the most widely used and popular peptides out there. I really do.

So personal story, obviously, I do jiu-jitsu most of the day. That's what I do. And I got a huge... Anyone listening to this podcast? I don't know if you can see over my eyebrow over here, you can't really see. That's the entire point. I got a huge gash under my eye, a completely open under my eyebrow. And shout out to Integrative Oasis, a way's spal in California, where I was vaguely aware of KPV, but it wasn't something that I thought you could just spray topically. He's like, Hey, you should do this. You should mix GHKCO-KPV, spray it on the injury site. And another Another thing is because there were some holiday, I don't remember what, but it was taped really badly. It wasn't stitched. Some ER doctor just taped over it. It looked horrible. When I say horrible, it looked like my one and a half year old did it. Something third-world country type, something not great. I sprayed it over it for eight weeks. People don't believe it. I show photos of the before and after. People think there is AI involved. It's insane.

Oh, man, I love hearing that. It's so cool to hear that because I think that while it's gaining steam, enough people don't know about it. I have a question for you.

Yeah.

Have you heard of Snap 8?

Of course, yeah. We use Snap 8 within the consideration of what we call neuromodulating peptides, which is basically you could think of mini topical botoxes. Yes. Arjarelin is the most widely used one, and lufacil probably is the most effective one. Snap 8, we found that when the skin is thinner, around the eyes, it works fantastically. And then when the skin is thicker, we need to use peptides that can have affinity to oil, to fat. So our Jerellin has a version of it that is oil-soluble, and lufosol, too, which makes it easier to use within that framework because around the eyes, you could get away with more like a hydrophilic, like a water-soluble peptides.

Yes.

By the Copper peptide, same things. Copper peptide, you could have another little molecule structure there, which makes it both loving water and oil. But when I mentioned before that we're really looking at ways to manipulate copper peptide to make it have better penetration, that's one of the things that we're doing.

Yes, 100%. I was telling when it was coming out and I was learning more about it, I said, If you're going to market this, you have to market it better than Botox, but you have to explain why and you have to get into it.

I'll tell you what I like the most out of the neuromodulator peptides. It is not... I'm biased. When I say I'm I am, what would speak to me or what would excite me is when you're going to talk to me about someone using a product for 3-5 years and then getting the full benefits. If you're telling me this was great after 12 weeks and you can't talk to me about further results, I'm not going to be as interested. And what is really cool about Neuromodulator. So what is really cool about those peptides, that what they're doing is they're sitting on the nerves that fire and make your muscles contract, and they're making them get tired really fast. Not, by the way, physically, but chemically. The thing that the The activity of them gets worn down very fast. So there's no adverse effect. We're just going through more conductive material faster. What happens is that You are also getting 10 to 20% of the results that Botox is. But more than that, you're getting non-repetitive folding of the skin. The way that we get wrinkles is like bending any flexible material in the same spot over and over and over again, you're weakening the material only where you bent it.

So by having the skin basically fold in different areas because other nerves are less tired, so they're going to be the ones who fire, you're accumulating less wrinkles over time. That's the important aspect for us. It's not only the, Oh, you're going to have less wrinkles after X amount of time. Yes, you get that, but you get other ones, those benefits as well. I hope I may have explained it well.

No, no. Perfect. Of course. I've been getting Botox for quite a long time, and I've tested different types, D-Sport, and the The last time I went, because I just moved cross country here, so I had to find a new place. The doctor I found literally the most incredible one that I've ever come across that does injections, and she's on a different level of intelligence. She said, Why don't you try this Daxify? Because it's peptide powdered. I tried it, and I really, really like it. I'm hoping that it was... I'm a fast responder to everything I do. I always have been, but I've noticed it really effect right away, and it's been really nice, and it was a nice alternative. I don't know anything about it. I'm just learning about it, but it's powered by some peptide, so I was definitely on board to try it. For the first time, I did a microneedling, but it was like the vampire one. I did the PRP, and man, I really noticed. I'm like, Shit, I'm going to be doing this.

Yeah. Two scoops. Yeah, so give it, fill me in. Two scoops. First scoop is actually a long longer term, we're working with a French company, really cool company. If anyone knows, shout out to OneSkin, our friends. They have a skincare company. Normally, we don't talk about competitors, but they're strict people. They're our friends. So what One Skin did is something really cool. They went over like 900 peptides, and they understood which peptides are going to work well for senescence. And then you obviously have a lot of science you need to go after that. But that's a good way to start. There is another French company who does it? Not going to mention their names because it's not ripe yet. I can't. But that does it instead of like 900 peptides, tens of thousands of peptides. The same thing that we're talking about with Daxify, where we're Using peptides to infiltrate the signaling system in our skin to stop some of the contractions from happening. This is literally the same, but you can apply it topically, and it would do it for collagen production. It's really, really cool. But it's going to take a while for us to integrate it.

But this company is amazing. Aside from the fact that it costs a fortune to do, which is our problem, it's a really cool That's a really cool endeavor. That's long term. But short term, since you mentioned vampire facial or PRP microneedling, basically, we're coming up, probably by the time this podcast, we're already going to have it out. We're coming out with PRP-derived exosome.

Really?

Yeah. What's insane about PRP-derived exosome is that most people don't understand that exosomes are not what you're looking for. Exosomes bring into the skin what you're looking for.

Right.

Which is Growth factors, proteins, and mainly micro-RNAs. Micro-rnas are basically the same thing that we've been talking about as far as peptides, like computer codes, but on a DNA level rather than on a cellular level. It's like a deeper, more profound impact. So when you talk about peptides, and exactly like peptides, there is a lot of different micro-RNAs. So the reason PRP-derived exosomes, which is the reason that you, by the way, got the results from that PRP facial that you have, is that this is the exosomes that are expressed when injury is happening. And exactly like we talked about BPC-157, what happens when the injury is happening? That's when we express collagen production, elastin production, we lower inflammation, we bring more blood, whatever that is. The further you go out, zoom out of it, if you do it from fat tissue, bone marrow, umbilical cord, or God forbid from plants, because that's useless, you're getting less and less close to that specific response. You get different responses. If you're talking about plants, you're going to get only antioxidant type micro-ornase. If you're talking about fat, you're going to get a really just health benefit as a whole, but you're not really communicating the language of, let's make more collagen over here, right?

Right.

So there are about six studies showing that PRP-derived or platelet-derived exosomes are comparable to having a PRP facial or a vampire facial just by applying it on. So you're basically doing vampire facial at home. And that's, by the way, this is really well substantiated.

I have to get my We're going to send you one.

Don't worry. And do you know how we're going to call them? How that product is called? I actually have just the bottle here. Let me see. That's our casing. So it's all.

No way. I love it. I had no idea. That was sweet. I brought that up then.

Perfect timing.

No, I heard it here first. That's right. One of the things that... Because I got introduced to you through a couple of people that I highly respect. Our conversation, when I met you, immediately, I was like, I told my wife, I fucking love this guy. When I left, you're just my guy. But I could tell listening to the passion, and aside from the obvious knowledge. That's a given when you start talking to you about it, but the passion that you had behind it, but the way that you guys, you and your wife, seem so innovative with the products, and you weren't just settling on a couple of things. A lot of these companies, they sell expensive products, and I never see anything different. When they do, it's rare, and it's not really innovative, and there's not a lot behind it. They're not looking for new methodologies, technologies, new ingredients or combinations It's whatever the case. I could tell that right away, and I was like, Man, this is how I operate. That's what drew me to you in the first place was the similarities in thinking and then the passion behind the concept, right?

Listen, to be honest, this is because we made it. This company is made for people like you or people who listen to this podcast. We're not for everyone. It's really okay. It's fine. I'm not saying, Oh, we're a Lamborghini or Ferrari and someone else is a Toyota. I'm not saying that. But the same way you're going to talk about cars, clothes, anything that people choose where they put their money in and they're not obligated for whatever reason, we are a company that is it's designed or that it's credo is innovation, coupled with well-substantiated science. Some other people, they care about different things. It could be, by the way, price. It could be that some people care about What's the least I can spend to get nice results? As we said, it's much cheaper to go to 80% than to 90%. That's right. Unfortunately, it costs a lot of money to I get to whatever, 95% or however you would describe us.

You didn't ask this, but I'm going to do this because I want to point this out, and this is why I brought this up, because I still use certain things. I incorporate a multifaceted regimen. I have some hypopigmentation, so I use an even and Correct, but I stop using Skinmedica, aside from that product. Then Timeline is my biggest partner, so I use their Serum and their creams. But I have a couple that I have of yours. One of them is this amplifying essence, and because it does such a multitude of things, and it's completely different than anything I've ever seen. And the other one that I love, because I'm a mask guy, is this one, this hyperbaric mask. Man, I love this. Every time I have an important thing, like last night before I did this, I lined myself up and I put this on. And I only use that when I got something really important, come in the day before. I don't think you should overuse masks, so to speak. But that thing, I love that, man. It is legit. And I'm a big fan of your cleanser. It's very gentle and it's nice on the skin, and I like that because look, it's like the people that tell me, Oh, all protein powders are the same.

I'm like, Bro, that is the most ridiculous thing I've ever heard. And it's the same thing with cleansers. You'll see a 50,000 of them, but there's so many different ones. I don't know the science behind all of it, but I do know the quality and the care and what's the ingredients.

Yeah, I 100% agree. Thank It's super nice to hear. Oh, yeah. We're going to have to get you to part two because we're here. I mean, it's been an hour and I blinked twice. I know. But I do want to ask you some rapid fire questions to try and cover many things that we didn't cover. Let's see if we can give quick answers here. Okay. What's the biggest mistake people make with skincare that reminds you of mistakes that people make in fitness?

Just the consistency. It's not staying consistent with eating and training, not staying consistent with doing your morning and evening regimen. Oh, I didn't do it today. It's fine. Or, I didn't do it the next day. Fine. Well, no, it's not. It's not fine.

Yeah, I agree. In the same vein of translating performance optimization to skin, what do you think is the most underrated habit for skin longevity that you learned from performance optimization.

Sleep, 100%. Sleep, and then not drinking alcohol. Those would be, yeah, I guess let's just call it lifestyle, but definitely is number one.

Well, alcohol also fucks up your sleep. Yeah, exactly. What do you wish more people knew about how hormones affect skin health and aging?

Well, anytime you're not hormonally optimized, everything's going to be off. You can take every skin product, you can take every supplement, you can take every GLP-1. I don't care what it is. If your hormones are messed up, it causes everything to be off. Really quick, when people take testosterone or steroids immediately, their hormones are messed up, acne, things like that start to come. And obviously, that's an influx of hormone. But if they're off, things like that, you're going to notice problems, and it'll show in your face and your skin.

Love it, yes. Let's talk about your model days. What is one thing that you learned during your early time as a person that makes a living off of how they look that you still do to this day and you feel like it's something that more people should know about.

It's really the regimen, man. It's like staying like we just talked about, the consistent regimen. I was partying a lot. I was doing a lot of things I shouldn't have been doing. I'd wake up late and be in a hurry, wouldn't do my scan. Over Over time, especially, you can get away with things when you're young to a point, but you can still see that that lack of consistency and accountability, man, it shows, and it shows fast.

Okay, last one. What breakthrough in biohacking do you think will change the way we approach longevity in the next five years?

I honestly think that peptides are going to become more mainstream, widely used, widely implemented, widely prescribed, and widely accepted. I think when that happens, you're going to see a drastic drastic change in health care and the amount of people actually needing to be staying on medications and in being into the system, so to speak. I think you'll see a drastic change when it's more widely acceptable.

I agree. And exactly like multi-use, multi-use preloaded pens right now that we're to see, I can't wait to see how much easier administer Diminishing String Peptides will be in five years.

I sat in on some conferences at A4M, and I've sat with some of the biggest, brightest, most intelligent scientists, and they're working on many different mechanisms of taking these Especially topical forms, and they're perfecting it, they're testing it, and they're working on it, and it will come. I mean, it certainly will. It takes time, but it's on the horizon. I've got people I'm going to be interviewing soon that are knee-deep into it.

Fantastic. Listen, Dylan, it's been almost as great as talking to in person. I super appreciate the time that you gave us, and I can't wait to do part two and to have many more conversations with you.

Dude, I love you. I love your wife. I love what you guys do. You know that my wife loves you guys, and it's just been meeting you has been so tremendous. Having somebody like you in my life is amazing, and I'm so glad I got the time to talk to you, man.

It's mutual. Last, before we go, how do people learn more, follow you, et cetera?

Yeah, my website's just about done. It's up. It's not fully complete. Dylangemeli. Com. My Dylan Gemeli podcast on Apple, and then I'm at Dylan Gemeli. Instagram is where I'm at. I have TikTok. Don't expect to get an answer from me there. But Instagram, I make it a point to do all of my own social media. I know a lot of people don't, and I do my damnest to get back to people the best I can.

That's impressive. Okay, Dylan, thank you again. It's been a pleasure. We will talk again soon.

Thanks, brother.

Bye. Take care.